Administration & Dosage
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PO, taken without regard to meals. 【Adult】 ● Generalized anxiety disorder; Major depressive disorder : *initial, 10 mg/d as a single dose in the morning or evening; *maintenance, 10 mg/d, may increase to 20 mg/d only after a minimum of 1wk. 【Pediatric ≧12yrs]】 ● Major depressive disorder : *initial, 10 mg/d as a single dose in the morning or evening; *maintenance, 10 mg/d, may increase to 20 mg/d only after a minimum of 3 wk.
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Adverse reaction
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【M】Headache, insomnia, drowsiness; nausea, diarrhea; ejaculatory disorder. 【L& R】Fatigue, dizziness, anorgasmia, abnormal dreams, lethargy, paresthesia, yawning; diaphoresis; decreased libido; menstrual disease; xerostomia, constipation, dyspepsia, decreased appetite, vomiting, abdominal pain, flatulence, toothache; Impotence, UTI; neck pain, shoulder pain, back pain; Flu-like symptoms, rhinitis, sinusitis, nasal congestion.
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